Dipotassium Glycyrrhizinate: A Powerful Natural Soothing Ingredient for Cosmetics and Personal Care

Dipotassium Glycyrrhizinate (also known as Potassium Glycyrrhizinate) is a highly effective active ingredient derived from licorice root extract (Glycyrrhiza glabra). It is widely used in cosmetic, pharmaceutical, and personal care formulations due to its excellent anti-inflammatory, skin-soothing, and anti-irritation properties.

As a water-soluble derivative of glycyrrhizic acid, it offers improved formulation compatibility, making it a preferred ingredient in modern skincare systems.

1. What is Dipotassium Glycyrrhizinate?

Dipotassium Glycyrrhizinate is a natural compound obtained from licorice root. It is the dipotassium salt of glycyrrhizic acid, which enhances its solubility and stability in aqueous systems.

This ingredient is widely recognized for its ability to calm irritated skin, reduce redness, and support skin barrier repair, making it a key active in sensitive skin formulations.

2. Key Functions and Benefits

2.1 Anti-Inflammatory Effect

Dipotassium Glycyrrhizinate helps reduce skin inflammation by inhibiting inflammatory mediators. It is commonly used in products targeting acne, dermatitis, and allergic skin reactions.

2.2 Skin Soothing and Calming

It provides immediate soothing effects, helping to relieve skin discomfort caused by external stress such as UV exposure, pollution, or chemical irritation.

2.3 Redness Reduction

This ingredient effectively reduces visible skin redness, making it ideal for sensitive skin and post-treatment skincare products.

2.4 Skin Barrier Support

It helps improve the skin’s natural defense system, supporting recovery from damage and maintaining long-term skin health.

2.5 Anti-Allergic Properties

Dipotassium Glycyrrhizinate is widely used in dermatological formulations due to its ability to reduce allergic responses and itching.

3. Applications

3.1 Cosmetics and Skincare Products

Dipotassium Glycyrrhizinate is extensively used in:

• Facial creams and lotions

• Serums and ampoules

• Sensitive skin care products

• Anti-acne formulations

• Sunscreen and after-sun care products

• Facial masks and cleansers

Its excellent compatibility with other cosmetic ingredients makes it suitable for a wide range of formulations.

3.2 Pharmaceutical Applications

In pharmaceutical formulations, it is used for:

• Anti-inflammatory topical creams

• Skin irritation treatments

• Dermatitis and eczema relief products

• Oral care products such as mouthwash and toothpaste

3.3 Personal Care Products

It is also used in:

• Shampoos and conditioners (scalp soothing)

• Body washes

• Hand creams for sensitive skin

4. Mechanism of Action

Dipotassium Glycyrrhizinate works by regulating inflammatory pathways in the skin. It helps inhibit the release of histamine and other inflammatory mediators, thereby reducing redness, swelling, and irritation.

Additionally, it supports skin hydration and barrier recovery, contributing to improved skin resilience over time.

5. Recommended Usage Level

• Cosmetics: 0.1% – 0.5%

• Leave-on products: Typically lower dosage for sensitive skin applications

• Rinse-off products: Can be used at slightly higher concentrations

6. Advantages Compared to Glycyrrhizic Acid

• Higher water solubility

• Better formulation stability

• Lower irritation potential

• Easier incorporation into modern cosmetic systems

7. Market Demand and Industry Trends

With the global rise in demand for clean beauty, natural cosmetics, and sensitive skin care products, Dipotassium Glycyrrhizinate has become a highly sought-after functional ingredient.

It is especially popular in:

• Korea and Japan skincare markets

• European natural cosmetics industry

• Fast-growing personal care markets in South America and Southeast Asia

8. Packaging and Supply

We supply high-quality Dipotassium Glycyrrhizinate with consistent purity and stable performance, suitable for industrial-scale cosmetic manufacturing.

• Standard packaging: 25 kg drum or customized packaging

• OEM and bulk supply available

9. Conclusion

Dipotassium Glycyrrhizinate is a versatile and highly effective cosmetic active ingredient that combines natural origin with powerful skin-soothing functionality. Its wide application in skincare, pharmaceutical, and personal care industries makes it an essential ingredient for modern formulations targeting sensitive and irritated skin.

COA - Dipotassium Glycyrrhinate - 260409A.pdf

TDS - Dipotassium Glycyrrhinate.pdf

MSDS - Dipotassium-glycyrrhizinate - Khonorchem.pdf